Ivo Karlovic defeated John Isner 7-6 6-7 7-6 in the Houston quarter-final on clay. The upset overturned the form book — John Isner came in defending last year's round of 16. Ivo Karlovic extended the head-to-head to 3–2.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2014-02-24 | Acapulco | R32 | hard | Ivo Karlovic | 7-6 7-6 |
| 2013-07-08 | Newport | QF | grass | John Isner | 7-6 7-6 |
| 2010-02-15 | Memphis | QF | hard | John Isner | 6-1 7-6 |
| 2008-08-17 | New Haven | R32 | hard | Ivo Karlovic | 6-7 6-3 6-4 |
Averages over each player's completed matches in the selected window (200 vs 200). ATP, WTA & Challenger.
Performance in the biggest moments — break points, deciding sets and tiebreaks (0–100, higher is better). About
Each player's serve crossed against the other's return, converted to expected hold of serve. Recent completed matches, ATP, WTA & Challenger. About