Mariana Duque Marino defeated Agustina Lepore 7-6 6-1 in the San Luis Potosi 25K round of 16 on hard. Mariana Duque Marino extended the head-to-head to 3–2.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2006-05-29 | Leon 10K | SF | hard | Agustina Lepore | 6-4 6-4 |
| 2006-05-08 | Los Mochis 10K | F | clay | Mariana Duque Marino | 6-2 6-1 |
| 2005-09-05 | Santiago 10K | R16 | clay | Agustina Lepore | 5-7 7-5 6-3 |
| 2005-08-22 | Bogota 10K | R16 | clay | Mariana Duque Marino | 6-7(5) 6-4 6-4 |
Averages over each player's completed matches in the selected window. ATP, WTA & Challenger.