Lourdes Dominguez Lino defeated Antonella Serra Zanetti 6-3 6-3 in the Palermo round of 32 on clay. The upset overturned the form book — Antonella Serra Zanetti came in leading the head-to-head 2–1, defending last year's round of 32. Lourdes Dominguez Lino narrowed the head-to-head to 2–2.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2000-06-12 | Grado 25K | R16 | clay | Lourdes Dominguez Lino | 6-2 6-3 |
| 2000-06-05 | Galatina 25K | SF | clay | Antonella Serra Zanetti | 7-5 6-2 |
| 1998-09-23 | Bucharest 25K | R16 | clay | Antonella Serra Zanetti | 6-1 6-2 |
Averages over each player's completed matches in the selected window. ATP, WTA & Challenger.