Rodrigo Guidolin defeated Marcelo Melo 6-3 1-6 7-6 in the Brazil F3 qualifying round on clay. The upset overturned the form book — Marcelo Melo came in leading the head-to-head 2–1. Rodrigo Guidolin narrowed the head-to-head to 2–2.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 2006-06-12 | Brazil F5 | R32 | clay | Rodrigo Guidolin | 6-2 5-7 6-3 |
| 2005-05-23 | Brazil F5 | R16 | clay | Marcelo Melo | 6-4 7-5 |
| 2004-11-15 | Brazil F14 | SF | clay | Marcelo Melo | 6-1 2-1 |
Averages over each player's completed matches in the selected window. ATP, WTA & Challenger.